Multihomed server capabilities allow administrators to specify up to four interfaces (either host names or IP addresses) in the FLDB for each File Server and FLDB machine. Servers can have more than four network connections; however, the FLDB can accept only four entries per server. This capability, coupled with server preference lists maintained by the individual Cache Managers, allows you to configure DFS to work optimally within your network.
For example, a single File Server can have up to four IP addresses (specified for use by DFS), and the various clients that use that server can have their Cache Manager preference lists configured so that the preferred access to that server is through the most efficient possible network connection. Should a single connection to a File Server become unavailable, the various clients that previously used that connection would consult their Cache Manager's preference lists and reroute their requests to another address for a File Server containing the required fileset. This lets you configure DFS for the most efficient use of the network while providing additional fail-over capabilities for the file system.
More:
How Multihomed Servers and Preferences Work Together
Tasks to Administer Multihomed Servers
IP Layer Override of Preferences
Creating Additional Default Entries in the Routing Table